Directed evolution of enzymes used for synthesis of pure enantiomers.

Journal is dedicated to bringing Darwin's dream-to "have fairly true genealogical trees of each great kingdom of Nature"-within grasp. Provides a forum for molecular studies that advance the understanding of phylogeny and evolution.

Details work exploring the evolution of novel ribozymes (deoxyribo and ribonucleic acid catalysts) from populations of random sequences, attempting to shed light on the origins of biological catalysis.

Transcript of chat with biochemist James Shapiro of the University of Chicago on his concept of "natural genetic engineering" at the cellular level.

This site explores the possibility that genetic variation and natural selection are two sides of a unitary and simultaneous response to the struggle for existence, as recent experiments at Harvard and elsewhere on bacteria imply.